||B-Tg(mAbcb1b) MC38||Catalog number||
md; Pgy; mdr; Abcb; Mdr1;
Pgy-; Pgy1; Abcb1; Mdr1b; Pgy-1
Subcutaneous homograft tumor growth of B-Tg(mAbcb1b) MC38 cells. B-Tg(mAbcb1b) MC38 cells (5x105) and wild-type MC38 cells (5x105) were subcutaneously implanted into C57BL/6 mice (female, 8-week-old, n=6). Tumor volume and body weight were measured twice a week. (A) Average tumor volume ± SEM. (B) Body weight (Mean± SEM). Volume was expressed in mm3 using the formula: V=0.5 X long diameter X short diameter2. As shown in panel A, B-Tg(mAbcb1b) MC38 cells were able to establish tumors in vivo and can be used for efficacy studies.